Not really!  But ghost 2003 will fit nicely on a boot floppy and Ghost 11.5 won't.
Only if you use Ghost 2003, from a floppy, will it offer to make your Ghost backup DVD bootable.  So that's a big plus if you're wanting a Bootable Ghost backup DVD.

If you want to back up Vista or Win-7, without having to do any weird stuff, or perform any acrobatics, Ghost 11.5 is your best bet.
Boot if from either a flash drive or Cd.  Works like a champ.

good luck,
Casper